Description of fourteen new DRB alleles found in a stem cell donor registry

Autor:	Robert J. Hartzman, Fu-Meei Robbins, A. Huang, L. Li, D. Sintasath, U. Heine, Carolyn Katovich Hurley, Y.-S. Lin, Jennifer Ng, T.F. Tang, G. Coquillard
Rok vydání:	2002
Předmět:	Genetics Immunology General Medicine Biology Biochemistry DNA sequencing Histocompatibility Stem cell donor Immunology and Allergy HLA-DRB5 Allele Sequence motif HLA-DRB1 HLA-DRB3
Zdroj:	Tissue Antigens. 59:63-65
ISSN:	0001-2815
DOI:	10.1034/j.1399-0039.2002.590115.x
Popis:	Fourteen DRB alleles, DRB1 * 0705, DRB1 * 11014, DRB1 * 1134, DRB1 * 1136, DRB1 * 1141, DRB1 * 1335, DRB1 * 1337, DRB1 * 1338, DRB1 * 1342, DRB1 * 1343, DRB1 * 1349, DRB1 * 1510, DRB3 * 0105, and DRB5 * 0103, are described. Among them,eleven are variants which differ by only one nucleotide from previously described alleles, including one silent variant (DRB1 * 11014). Alleles, DRB1 * 0705, DRB1 * 1335 and DRB3 * 0105, display unique sequence motifs that have never been observed in DRB alleles.
Databáze:	OpenAIRE
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