Le Test De Tolerance Au Chlorpropamide Intraveineux*
| Autor: | A. Elewaut, F. de Loose |
|---|---|
| Rok vydání: | 1962 |
| Předmět: |
Chlorpropamide
Pancreatic Insulinoma Drug medicine.medical_specialty business.industry media_common.quotation_subject General Medicine medicine.disease medicine.anatomical_structure Endocrinology Diabetes mellitus Internal medicine medicine Pancreatitis Endocrine system Pancreas business Insulinoma medicine.drug media_common |
| Zdroj: | Acta Clinica Belgica. 17:450-456 |
| ISSN: | 2295-3337 1784-3286 |
| DOI: | 10.1080/17843286.1962.11717720 |
| Popis: | SummaryA single dose of 500 mg of chlorpropamide was injected intravenously in each individual of a group of 62 subjects including I0 normal individuals without a familial history of diabetes.The drug induced a mean fall of 25 to 30 % in fasting blood glucose level in the normal subjects. This drop did not amount a mean value of 20 % in patients with true diabetes, latent diabetes or chronic pancreatitis. Contrastingly, in a case of insulinoma, the drug markedly enhanced the hypo-glycaemic tendencies.It is concluded that the intravenous chlorpropamide test is useful for studying the endocrine function of the pancreas. This test can detect latent diabetes as well as pancreatic insulinoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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