CBView: Merging Data in Metabolic Diagnosis
| Autor: | Rui Fonseca-Pinto, Marlene Lajes, Maria P. Guarino, Gabriel Correia Brito, Nuno Vieira Lopes |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Computer science Early detection 030209 endocrinology & metabolism Disease medicine.disease Bioinformatics Meal ingestion Pathophysiology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Insulin resistance medicine General Earth and Planetary Sciences medicine.symptom Metabolic syndrome Weight gain Homeostasis General Environmental Science |
| Zdroj: | Procedia Computer Science. 138:244-249 |
| ISSN: | 1877-0509 |
| DOI: | 10.1016/j.procs.2018.10.035 |
| Popis: | The metabolic syndrome is a set of risk factors associated with increased cardiovascular risk. These changes to the standard metabolic functions are associated with increased blood insulin and with insulin resistance, which is the common feature of disease pathophysiology. Although with admissible genetic inheritance, the metabolic syndrome symptoms increase with age, sedentarism, weight gain, tobacco, and poor dietetic habits. Due to their characteristics, clinical manifestations of metabolic diseases are perceived by the patient at advanced stages of metabolic dysfunction, when the risk of an acute cardiovascular event is high. Early detection of disturbed glucose homeostatic mechanisms, by recording efferent responses to stimuli like meal ingestion, is, therefore, a methodology with diagnostic potential acting as a predictive measure of metabolic dysfunction. This work presents a novel software (CBView) that analyses the records of physiological responses mediated by the carotid bodies to provocation tests, obtained by a new medical device (CBMeter) aiming to the early tracking of changes in autonomic responses that control metabolism, and thus providing quantitative metrics to assess metabolic dysfunction. |
| Databáze: | OpenAIRE |
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