Preparation and In Vitro Evaluation of Nerve Conduit Using Electro-Spun Biodegradable Polymers
| Autor: | Chong Pyong Chung, Hong Ki Bae, Dong June Chung |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Materials science
Mechanical Engineering Regeneration (biology) technology industry and agriculture Nerve guidance conduit Poly-p-dioxanone Biodegradable polymer In vitro PLGA chemistry.chemical_compound surgical procedures operative Electrical conduit chemistry Mechanics of Materials Mechanical strength cardiovascular system General Materials Science cardiovascular diseases health care economics and organizations Biomedical engineering |
| Zdroj: | Key Engineering Materials. :325-328 |
| ISSN: | 1662-9795 |
| DOI: | 10.4028/www.scientific.net/kem.342-343.325 |
| Popis: | In this study, we find out the possibilities to make conduit for nerve regeneration using biodegradable polymers, which have enough mechanical strength in surgery. Cell adhesion (PC12) behaviors about various nerve conduits have not great difference compared to control. This is regarded due to specific structure of nerve conduits formed nano-fibers. In the case of PPD, we observed better phenotype of adhered cell than PLGA samples. Also, PPD-PLGA bi-layered nerve conduits were more effective than PLGA nerve conduit for in vitro evaluation. |
| Databáze: | OpenAIRE |
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