Preparation and spectroscopic properties of 2′,5′-dideoxynucleosidylcobalamins

Autor:	Hongzhe Sun, Hong Yan, De‐Ping Xie, Huilan Chen, Wen-Xia Tang
Rok vydání:	2010
Předmět:	1h nmr spectroscopy Computational chemistry Chemistry Stereochemistry Improved method General Chemistry Coenzyme B12
Zdroj:	Chinese Journal of Chemistry. 12:33-42
ISSN:	1001-604X
DOI:	10.1002/cjoc.19940120105
Popis:	Two new coenzyme B12 analogues, 2′,5′-dideoxycytidylcobalamin (2a) and 2′,5′-dideoxyuridinylcobalamin (2b), and two others, 2′,5′-dideoxyadenosylcobalamin (2c), and 5′-deoxythymidylcobalamin (2d) were prepared by an improved method. All the four analogues were investigated by UV-vis and 2D 1H NMR spectroscopy. The comparisons and discussion about their spectroscopic properties were done.
Databáze:	OpenAIRE
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