ADVANCED TREATMENT IN RHEUMATOID ARTHRITIS. IS IT POSSIBLE TO TAPER THE BIOLOGICAL TREATMENT?

Autor:	Catalina Raluca Nuta, Ina Cambu, Pharmacy, Bucharest, Romania, Denisa Predeteanu
Rok vydání:	2015
Předmět:	medicine.medical_specialty business.industry Rheumatoid arthritis Medicine General Materials Science business medicine.disease Dermatology
Zdroj:	Romanian Journal of Rheumatology. 24:189-193
ISSN:	2069-6086 1843-0791
DOI:	10.37897/rjr.2015.4.1
Popis:	Rheumatoid arthritis (RA) is a systemic autoimmune disease, leading to synovial hypertrophy and adjacent bone and cartilage destruction. The combined use of biological agents and methotrexate (MTX) has revolutionised the treatment of RA producing significant improvements in clinical, radiographic and functional outcomes. The results of clinical study and experience of the specialities of rheumatology in clinical statement showed the long treatment may be associated with side effects, in addition biological treatment means high cost. The next goal should be remission without the use of biological agents. That’s why new treatment in RA means the tapering or even stopping the biological treatment in patients with RA who reached remission. In association with the new recommendation EULAR in 2013 there are many studies which showed the possibility of tapering or discontinuing the biological therapy in patients in sustained remission.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4fc4ab9356dab49920cb9ed975175a83 https://doi.org/10.37897/rjr.2015.4.1 Zobrazit plný text záznamu Plný text ve formátu PDF