One-Pot Three-Component Condensations of 2,6-Diaminopyrimidin-4(3H)-one, Aromatic Aldehydes, and Naphthols. Synthesis of Isomeric Benzochromeno[2,3-d]pyrimidines

Autor:	A. A. Harutyunyan, Henry A. Panosyan, S. G. Israyelyan, T. R. Hovsepyan
Rok vydání:	2020
Předmět:	chemistry.chemical_compound Pyrimidine 010405 organic chemistry Chemistry Organic Chemistry Hydroxy group Ring (chemistry) 01 natural sciences Medicinal chemistry 0104 chemical sciences
Zdroj:	Russian Journal of Organic Chemistry. 56:1211-1216
ISSN:	1608-3393 1070-4280
DOI:	10.1134/s1070428020070143
Popis:	One-pot three-component reactions of 2,6-diaminopyrimidin-4-(3H)-one with aromatic aldehydes and 1- or 2-naphthol afforded benzo[7,8]chromeno[2,3-d]pyrimidine and benzo[5,6]chromeno[2,3-d]pyrimidine derivatives, respectively. In both cases, the heterocyclization involved substitution of the 6-amino group of 2,6-diaminopyrimidin-4-(3H)-one by hydroxy group of naphthol and closure of 4H-pyran ring, whereas no alternative benzopyrimidoquinoline derivatives were formed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4fc39e9b3bd68aba35f0a21e3a3bfbc1 https://doi.org/10.1134/s1070428020070143 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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