A STUDY OF STAGE IV GASTRIC CANCER
| Autor: | Kikuo Koufuji, Jinryo Takeda, Yasuhiro Terasaki, Shojiro Yano, Haruko Hori, Kazuo Shirouzu, Keishiro Aoyagi, Naotaka Murakami |
|---|---|
| Rok vydání: | 2000 |
| Předmět: | |
| Zdroj: | Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 61:1128-1134 |
| ISSN: | 1882-5133 1345-2843 |
| DOI: | 10.3919/jjsa.61.1128 |
| Popis: | We studied stage IV gastric cancer cases in our department, and 3-year survial cases. Of 17 cases that were 3-year survival cases, 15 underwent curative B operations, one case underwent curative C operation due to ow (+), and all operative cases were H0, P0. In 3-year survival cases, the number of metastatic group 3 lymph nodes in n3 cases was up to 2 nodes, the number of metastatic group 3 and 4 lymph nodes in n4 cases was up to 3 nodes. Many of the 3-year survival cases underwent postoperative combined chemotherapy with MMC, fluorouracil and immunotherapy. Moreover, one inoperable 3-year survival case got complete response from combined immunochemotherapy with MMC, 5' DFUR and OK-432. These results suggest that to promote long-term survival in stage IV gastric cancer cases, curative B operation and postoperative immunochemotherapy are indicated in cases that have P0, H0 and some metastasis to group 3 or 4 lymph nodes histologically. The prognosis for P(+) and H(+) cases is still poor, and multi-disciplinary treatments including neoadjuvant chemotherapy are recommended for these as well as for cases that have many metastases of group 3 or 4 lymph nodes on preoperative examination. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|