A case-control study of smoking and sudden infant death syndrome in the Scandinavian countries, 1992 to 1995

Autor: Bernt Alm, J Milerad, Trond Markestad, Lorentz M. Irgens, G. Norvenius, Nina Øyen, Rolv Skjærven, Karin Helweg-Larsen, Göran Wennergren, Anne Kjersti Daltveit
Rok vydání: 1998
Předmět:
Zdroj: Archives of Disease in Childhood. 78:329-334
ISSN: 1468-2044
0003-9888
DOI: 10.1136/adc.78.4.329
Popis: Aim—To establish whether smoking is an independent risk factor for sudden infant death syndrome (SIDS), if the eVect is mainly due to prenatal or postnatal smoking, and the eVect of smoking cessation. Methods—The analyses were based on data from the Nordic epidemiological SIDS study, a case-control study with 244 cases and 869 controls. Odds ratios were computed by conditional logistic regression analysis. Results—Smoking emerged as an independent risk factor for SIDS, and the eVect was mainly mediated through maternal smoking in pregnancy (crude odds ratio 4.0 (95% confidence interval 2.9 to 5.6)). Maternal smoking showed a marked dose‐response relation. There was no eVect of paternal smoking if the mother did not smoke. Stopping or even reducing smoking was beneficial. SIDS cases exposed to tobacco smoke were breast fed for a shorter time than non-exposed cases, and feeding diYculties were also more common. Conclusions—Smoking is an independent risk factor for SIDS and is mainly mediated through maternal smoking during pregnancy. Stopping smoking or smoking less may be beneficial in reducing the risk of SIDS. (Arch Dis Child 1998;78:329‐334)
Databáze: OpenAIRE