FEMALE PSEUDOHERMAPHRODISM WITH PENILE URETHRA, MASQUERADING AS PRECOCIOUS PUBERTY AND CRYPTORCHIDISM
| Autor: | H. Lisser, William A. Reilly, Richard C. Bentinck |
|---|---|
| Rok vydání: | 1956 |
| Předmět: |
Gynecology
medicine.medical_specialty urogenital system business.industry Endocrinology Diabetes and Metabolism Virilization Biochemistry (medical) Clinical Biochemistry Uterus Labia majora medicine.disease Biochemistry Endocrinology medicine.anatomical_structure Urethra Labia minora Internal medicine medicine Vagina Precocious puberty medicine.symptom business Cervix |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 16:412-418 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-16-3-412 |
| Popis: | Female pseudohermaphrodism is characterized by varying degrees of masculinization of wolffian and mullerian derivatives, present at birth, in a gonadal female. Subsequently, other somatic and secondary sexual characteristics deviate toward the masculine and may appear precociously. Typically, the female pseudohermaphrodite at birth has an enlarged nonperforate phallus with a single opening (urogenital sinus) at its base, large, empty scrotum-like labia majora and absent or vestigial labia minora. The urethra and a short vagina open into the urogenital sinus. The cervix, uterus, tubes and ovaries may be fully or incompletely developed. Prostatic elements may be present. Such a combination of virilization and relatively obvious developmental abnormalities of the external genitalia will, on clinical grounds, indicate the necessity of differentiating a female pseudohermaphrodite from a hypospadiac male with sexual precocity and cryptorchidism. |
| Databáze: | OpenAIRE |
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