Physiological and metabolic differences between visceral and subcutaneous adipose tissues in Nile tilapia(Oreochromis niloticus)
| Autor: | Jilei Zhang, Samwel Mchele Limbu, Dong-Liang Li, Jian-Gang Jiao, Mei-Ling Zhang, Zhen-Yu Du, Xiaoxia Du, Fang Qiao, Ya-Wen Wang |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Physiology Adipose tissue 03 medical and health sciences Nile tilapia chemistry.chemical_compound Physiology (medical) Adipocyte Internal medicine parasitic diseases Brown adipose tissue medicine chemistry.chemical_classification biology nutritional and metabolic diseases Fatty acid 04 agricultural and veterinary sciences biology.organism_classification Oreochromis 030104 developmental biology medicine.anatomical_structure Endocrinology chemistry Biochemistry Adipogenesis 040102 fisheries 0401 agriculture forestry and fisheries tissues human activities Polyunsaturated fatty acid |
| Zdroj: | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 313:R608-R619 |
| ISSN: | 1522-1490 0363-6119 |
| DOI: | 10.1152/ajpregu.00071.2017 |
| Popis: | Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SCAT) have different structures and metabolic functions and play different roles in the regulation of the mammal endocrine system. However, little is known about morphology and physiological and metabolic functions between VAT and SCAT in fish. We compared the morphological, physiological, and biochemical characteristics of VAT and SCAT in Nile tilapia and measured their functions in energy intake flux, lipolytic ability, and gene expression patterns. SCAT contained more large adipocytes and nonadipocytes than VAT in Nile tilapia. VAT had higher lipid content and was the primary site for lipid deposition. Conversely, SCAT had higher hormone-induced lipolytic activity. Furthermore, SCAT had a higher percentage of monounsaturated and lower polyunsaturated fatty acids than VAT. SCAT had higher mitochondrial DNA, gene expression for fatty acid β-oxidation, adipogenesis, and brown adipose tissue characteristics, but it also had a lower gene expression for inflammation and adipocyte differentiation than VAT. SCAT and VAT have different morphological structures, as well as physiological and metabolic functions in fish. VAT is the preferable lipid deposition tissue, whereas SCAT exhibits higher lipid catabolic activity than VAT. The physiological functions of SCAT in fish are commonly overlooked. The present study indicates that SCAT has specific metabolic characteristics that differ from VAT. The differences between VAT and SCAT should be considered in future metabolism studies using fish as models, either in biomedical or aquaculture studies. |
| Databáze: | OpenAIRE |
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