Fractal geometry of coronary plaque images within optical coherence tomography: A novel approach of plaque vulnerability in patients with acute coronary syndrome versus stable angina pectoris

Autor: Tomoyuki Morikawa, Takafumi Hiro, Takashi Mineki, Keisuke Kojima, Takaaki Kogo, Korehito Iida, Naotaka Akutsu, Nobuhiro Murata, Mitsumasa Sudo, Daisuke Kitano, Daisuke Fukamachi, Yasuo Okumura
Rok vydání: 2023
Popis: Background and Purposes: The main cause of acute coronary syndrome (ACS) is plaque rupture and thrombus formation. However, it has not been fairly successful to identify vulnerable plaque to rupture using conventional parameters of intravascular imaging modalities. Fractal analysis is one of the mathematical models to examine geometrical features of picture image using a specific parameter called as fractal dimension (FD) which suggests geometric complexity of the image. This study examined FD of the optical coherence tomography (OCT)-derived images of the culprit plaque in patients with ACS versus stable angina pectoris (SAP) in order to evaluate the feasibility of FD for identifying vulnerable coronary plaques, because coronary plaques in ACS patients are known to be more vulnerable than those in patients with SAP. Methods and Results We examined 65 cases (34 ACS patients, 31 SAP patients) in which the culprit lesion was imaged by OCT before percutaneous coronary intervention in patients with ACS and SAP. The culprit plaque lesion in the ACS group had a significantly larger mean lipid arc (203.8 ± 39.4° vs 152.3 ± 34.5°, p
Databáze: OpenAIRE