3,3′-dinitro-octahydrobinaphthol: A new chiral ligand for metal-catalyzed enantioselective reactions

Autor:	Joachim Rudolph, Manfred T. Reetz, Claudia Merk, Nils Griebenow, Guido Naberfeld, Richard Goddard
Rok vydání:	1997
Předmět:	Organic Chemistry Chiral ligand Enantioselective synthesis Sulfoxide Biochemistry Catalysis Metal chemistry.chemical_compound chemistry visual_art Drug Discovery visual_art.visual_art_medium Organic chemistry Enantiomer
Zdroj:	Tetrahedron Letters. 38:5273-5276
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(97)01149-0
Popis:	Starting from R -configurated binaphthol the R -form of the title compound was readily prepared in two steps and characterized by X-ray structural analysis. It was used as the chiral ligand in the Ti-catalyzed asymmetric oxidation of methyl-p-tolylsulfide, the S -enantiomeric form of the sulfoxide being formed preferentially (ee = 86%).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4f78de7d33955a0bb1d276e7ccedc86e https://doi.org/10.1016/s0040-4039(97)01149-0 Zobrazit plný text záznamu Full Text from ScienceDirect