Change in Mitral Annular Size and Geometry after MitraClip® Implantation in Patients with Functional and Degenerative Mitral Regurgitation

Autor: Talea Remy, Nina Wunderlich, Stefan Bertog, Sameer Gafoor, Ilona Hofmann, Laura Vaskelyte, Horst Sievert
Rok vydání: 2014
Předmět:
Zdroj: Journal of Interventional Cardiology. 27:516-524
ISSN: 0896-4327
DOI: 10.1111/joic.12145
Popis: Background MitraClip® therapy is an alternative to conventional surgery. The aim was to characterize the mitral annular geometry pre- and postrepair with the MitraClip® taking into account the regurgitation mechanism. Methods We retrospectively collected pre- and postprocedural transesophageal echocardiography data in 46 patients. Patients were categorized as having isolated degenerative (DMR, n = 18), isolated functional (FMR, n = 9) or a combination of both functional and degenerative mitral regurgitation (MMR, n = 19). Results A significant reduction in septolateral (SL) diameters in all patients occurred. Noteworthy, in those with DMR, there was no significant change in intercommissural (IC) diameters whereas in those with FMR and MMR, it increased significantly in systole (FMR: +2.8 ± 3.4 mm, P = 0.03, MMR: +2.1 ± 2.6 mm, P = 0.002). In DMR, a significant reduction in mitral annular areas post-procedure was observed (−1.8 ± 2.3 cm2, P = 0.001 in diast., −0.8 ± 1.0 cm2, P = 0.004 in syst.). In patients with FMR and MMR, though the SL diameter decreased, this occurred at the expense of an increase in IC diameter causing a change in annular shape but leaving the annular area unchanged. Nevertheless, a comparable reduction in regurgitant severity (DMR: P =
Databáze: OpenAIRE
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