ChemInform Abstract: Enantioselective Synthesis of Aryl Sulfoxides via Palladium-Catalyzed Arylation of Sulfenate Anions

Autor:	Giovanni Poli, Guillaume Maitro, Sophie Vogel, Mounel Sadaoui, Guillaume Prestat, David Madec
Rok vydání:	2008
Předmět:	chemistry.chemical_compound Enantiopure drug Chemistry Ligand Aryl Enantioselective synthesis chemistry.chemical_element General Medicine Combinatorial chemistry Palladium Catalysis
Zdroj:	ChemInform. 39
ISSN:	1522-2667 0931-7597
Popis:	Arylation of various sulfenate anions generated from β-sulfinyl esters by retro-Michael reaction in the presence of palladium(0) and enantiopure ligands gave the corresponding aryl sulfoxides in enantio-enriched form. The Josiphos-type ligand (R)-(S)-PPF-t-Bu2 turned out to be the best ligand tested, allowing ee's up to 83% in a predictable sense.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4f3ba7a71aaf957a34303843e1976fe3 https://doi.org/10.1002/chin.200822090 Zobrazit plný text záznamu Plný text