A neurodevelopmental origin of behavioral individuality in the Drosophila visual system

Autor:	Andrew Straw, Peter Robin Hiesinger, Bassem A. Hassan, Suchetana Bias Dutta, Liz Hellbruegge, Maheva Andriatsilavo, Guangda Liu, Gerit A. Linneweber, Mercedes Bengochea, Mathias F. Wernet, Radoslaw K. Ejsmont
Rok vydání:	2020
Předmět:	0303 health sciences Multidisciplinary Brain development biology media_common.quotation_subject Stochastic variation Object (grammar) biology.organism_classification Behavioral variation 03 medical and health sciences 0302 clinical medicine Variation (linguistics) Contrast (vision) Drosophila melanogaster Drosophila Neuroscience 030217 neurology & neurosurgery 030304 developmental biology media_common
Zdroj:	Science. 367:1112-1119
ISSN:	1095-9203 0036-8075
DOI:	10.1126/science.aaw7182
Popis:	Diversity from development When given a line to follow, some fruit flies do so carefully and others weave. Linneweber et al. now show that these behaviors are stable for an individual but diverse in an isogenic population. Key to generating individual diversity in the population is the inherent chaos of normal development. A set of neurons in the visual system is wired up in a variable manner, resulting in brain circuit asymmetry unique to each fly that guides its line-walking behavior. With more asymmetry in its brain circuit, a fly is better able to orient to the line. Science , this issue p. 1112
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4f24652086e000fd35c5b1db5a2ac834 https://doi.org/10.1126/science.aaw7182 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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