Homocysteine and Malondialdeyde (MDA) Levels Associated with the Occurrence of Cardiovascular Disease (CVD) in Chronic Renal Failure (CRF) in Malaysia
| Autor: | Zalinah Ahmad, Huzwah Khaza'ai, Zarida Hambali, Shahin Arab |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Creatinine
medicine.medical_specialty Homocysteine medicine.diagnostic_test business.industry medicine.medical_treatment General Medicine Disease Malondialdehyde Gastroenterology chemistry.chemical_compound High morbidity Endocrinology chemistry Internal medicine medicine Chronic renal failure business Lipid profile Dialysis |
| Zdroj: | Global Journal of Health Science. 3 |
| ISSN: | 1916-9744 1916-9736 |
| Popis: | Introduction: Atherosclerosis and following cardiovascular disease (CVD) are known as important reasons of the increased morbidity and mortality observed in patients with chronic renal failure (CRF). The association of serum malondialdehyde (MDA), homocysteine as well as other cardiovascular risk factors in relation to existence and cause of CVD were investigated. Methods: In these study 66 CRF patients without dialysis and 107 patients receiving dialysis were recruited and further stratified into group with CVD and without CVD as case groups. Those without renal failure and CVD were assigned as control group (n=33). Results: The patients with CRF showed a significant increase in plasma levels of MDA, homocysteine and C-reactive protein (CRP) compared to control. The positive association were observed between homocysteine, creatinine and MDA (all p |
| Databáze: | OpenAIRE |
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