Colloid volume loading does not mitigate decreases in central blood volume during simulated haemorrhage while heat stressed

Autor: Morten Bundgaard-Nielsen, F. Andersen, Birger Hesse, Thomas Seifert, J. Marving, Craig G. Crandall, Thomas Levin Klausen, Thad E. Wilson, Niels H. Secher
Rok vydání: 2012
Předmět:
Zdroj: The Journal of Physiology. 590:1287-1297
ISSN: 0022-3751
Popis: Key points • The capacity for humans to withstand a haemorrhagic challenge is reduced while heat stressed. • Identification of changes in central blood volume during simulated haemorrhage may help identify the mechanisms by which tolerance to haemorrhage is reduced during heat stress. • We found that the magnitude of reduction in central blood volume to a simulated hemorrhagic challenge is approximately three fold greater when individuals are heat stressed. • Volume loading did not change the relative magnitude of the reduction in central blood volume to that simulated haemorrhagic challenge. • These data show that greater reductions in central blood volume during a simulated haemorrhagic challenge while heat stressed may be a primary mechanism for impaired capacity to withstand that challenge in this thermal condition.
Databáze: OpenAIRE