Effect of Steroid Hormones on Sulfated Oviductal Glycoprotein Secretion by Oviductal Explants in Vitro1

Autor:	Gene Oliphant, Terry T. Turner, Moira F. Erickson-Lawrence, Ted S. Thomas
Rok vydání:	1989
Předmět:	medicine.medical_specialty animal structures Lagomorpha biology medicine.drug_class Embryo Cell Biology General Medicine biology.organism_classification Endocrinology Reproductive Medicine Cell culture Estrogen Internal medicine medicine Oviduct Secretion Explant culture Hormone
Zdroj:	Biology of Reproduction. 40:1311-1319
ISSN:	1529-7268 0006-3363
DOI:	10.1095/biolreprod40.6.1311
Popis:	Explants of rabbit ampullary and isthmic tissue were cultured 4 days with and without exogenous steroids, and the sulfated oviductal glycoprotein (SOG) concentration in the explant culture supernatants was determined. Tissues cultured with progesterone plus estrogen secreted significantly more SOG than control tissues, whereas tissues cultured with estrogen alone did not. Ampullary tissues cultured with progesterone plus estrogen secreted significantly more SOG than control tissues on Days 2 and 3, whereas SOG secretion by isthmic tissues was significantly above control secretion on Day 4. Ampullary and isthmic tissues differed significantly in their secretory capacity. Maximum ampullary SOG secretion was approximately 650 ng SOG/mg tissue/day. Maximum isthmic SOG secretion was approximately 30 ng SOG/mg tissue/day. These findings suggest that the oviduct is composed of discrete functional regions that provide support to gametes and developing embryos through the unique secretory characteristics of each region.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4ee1926ba095e9a5ce52aaf8e4618107 https://doi.org/10.1095/biolreprod40.6.1311 Zobrazit plný text záznamu