Synthesis of 2,5-diaryl-4-halo-1,2,3-triazoles and comparative study of their fluorescent properties

Autor:	Sema L. Ioffe, Vladimir A. Motornov, Valentine G. Nenajdenko, Andrey A. Tabolin, Nikolay E. Shepel, Roman A. Novikov
Rok vydání:	2018
Předmět:	010405 organic chemistry Chemistry Organic Chemistry Regioselectivity Quantum yield 010402 general chemistry 01 natural sciences Biochemistry Fluorescence 0104 chemical sciences Coupling (electronics) Computational chemistry Drug Discovery Halo
Zdroj:	Tetrahedron. 74:3897-3903
ISSN:	0040-4020
DOI:	10.1016/j.tet.2018.05.071
Popis:	A convenient method for arylation of mono- and disubstituted 1,2,3-triazoles by copper-catalyzed Chan-Lam coupling was developed. The method is applicable for the regioselective synthesis of fluorescent 4-halogen-substituted (Hal = F, Cl, Br) 2,5-diaryl-1,2,3-triazoles in high yields. Comparative study of their fluorescent properties revealed that 4-fluorosubstituted triazoles possess the highest quantum yield (up to 0.69) among halogenated triazoles possessing Cl and Br in the position 4.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4edd10c89f4e05ffedae0d3a7294e9b8 https://doi.org/10.1016/j.tet.2018.05.071 Zobrazit plný text záznamu Full Text from ScienceDirect