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Acute toxicity and effect of aqueous leaf extract of Jatropha curcas (ALEOJC) on carbon tetrachloride (CCl 4) induced hepatotoxicity in albino rats was evaluated. The rats (60) were divided into five groups designated as; I, II, III, IV and Vof which groups I and II has 15 rats each while, group III, IV and V have 10 rats each. Groups II to V were induced with hepato-toxicity using 150 mg/kg body weight CCl 4 intramuscularly. Serum liver marker enzymes were assayed 48hrs after induction of liver injury followed by 2 nd and 4 th weeksof treatment with ALEOJC and Livolin. Oral LD 50 of ALEOJC was found to be 2,792.85 mg/kg. Serum levels of alanine amino transferase (ALT), Aspartate amino transferase (AST), Alkaline Phosphatase (ALP) and bilirubin level were significantly (P |
