4-Hydroxy-2-quinolones. 194*. 1-Hydroxy-3-oxo-6,7-dihydro-3H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid alkylamides. Synthesis, structure, and biological properties

Autor:	O. V. Gorokhova, K. V. Andreeva, Igor V. Ukrainets, N. Yu. Golik
Rok vydání:	2011
Předmět:	chemistry.chemical_classification Steric effects chemistry.chemical_compound chemistry Carboxylic acid Biological property Organic Chemistry Quinoline Organic chemistry Ethyl ester Diuretic Activity
Zdroj:	Chemistry of Heterocyclic Compounds. 46:1459-1466
ISSN:	1573-8353 0009-3122
DOI:	10.1007/s10593-011-0692-5
Popis:	Modified methods are proposed for the preparation of the ethyl ester and alkylamides of 1-hydroxy-3-oxo-6,7-dihydro-3H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid. A comparative analysis has been carried out of the steric structure and diuretic activity of the synthesized compounds and the previously studied, and closely structurally related, 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo-[3,2,1-ij]quinoline-2-carboxamides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4eca9b970aaf0b36517c47c9ba520984 https://doi.org/10.1007/s10593-011-0692-5 Zobrazit plný text záznamu Plný text ve formátu PDF