Double Michael Addition Reactions of the Nazarov Reagent with 2-Cyano-2-Cycloalkenones: An Alternative Approach to cis-Fused Bicyclic Systems

Autor:	Kak Shan Shia, Min-Tsang Hsieh, Yen-Ku Wu, Hsing-Jang Liu, Che Hao Tu, Sheng-Chu Kuo
Rok vydání:	2013
Předmět:	Annulation Bicyclic molecule Chemistry Reagent Organic Chemistry Michael reaction Stereoselectivity Combinatorial chemistry Catalysis
Zdroj:	Synlett. 25:543-546
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0033-1340299
Popis:	A highly stereoselective annulation reaction of 2-cyano-2-cycloalkenones with the Nazarov reagent catalyzed by 1,8-diaza­bicyclo[5.4.0]undec-7-ene (DBU), leading to densely functionalized bicyclic systems, is developed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4eb71a56dc76a2169ff16d7e5c6c8347 https://doi.org/10.1055/s-0033-1340299 Zobrazit plný text záznamu