Toward scalable in vitro models: a novel experimental and computational pipeline for the identification of cellular metabolic parameters

Autor: Arti Ahluwalia, Ermes Botte, Chiara Magliaro, Piera Mancini
Rok vydání: 2021
Předmět:
Zdroj: Biomedical Science and Engineering. 4
ISSN: 2531-9892
DOI: 10.4081/bse.2021.179
Popis: Oxygen utilization by cells has a crucial role in the design of advanced in vitro models. The aim of this study is to develop an experimental and computational pipeline for identifying oxygen metabolism parameters. We applied the approach to HepG2 cell monolayer cultures, demonstrating that such parameters depend on cell density.
Databáze: OpenAIRE