Effect of Neutral Pyridine Leaving Groups on the Mechanisms of Influenza Type A Viral Sialidase-Catalyzed and Spontaneous Hydrolysis Reactions of α-d-N-Acetylneuraminides

Autor:	Andrew J. Bennet, Doug T. H. Chou, Andrew A. Scholte, Thor J. Borgford,‡ and, Jacqueline N. Watson
Rok vydání:	2000
Předmět:	chemistry.chemical_classification Stereochemistry General Chemistry Sialidase Biochemistry Catalysis chemistry.chemical_compound Colloid and Surface Chemistry Enzyme chemistry Reagent Pyridine Pyridinium Spontaneous hydrolysis
Zdroj:	Journal of the American Chemical Society. 122:8357-8364
ISSN:	1520-5126 0002-7863
DOI:	10.1021/ja001641x
Popis:	A reagent panel, comprised of five pyridinium salts of α-d-N-acetylneuraminic acid, was synthesized and then used to probe enzymatic (α-sialidase) and nonenzymatic mechanisms of neuraminide hydroly...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4ea9612c854f961d1239ce2ae1fdf2e9 https://doi.org/10.1021/ja001641x Zobrazit plný text záznamu