Depistage De L’anemie En Urgence Au Chu Campus : Validation Du Degre De Concordance Entre Les Resultats De L’hemocue® Hb 301 Et Ceux Du Sysmex Xn-1000®
| Autor: | Micheline A .H. N Tettekpoe, Agboka Sogbéli Hounogbe, Gnatoulma Katawa, Kafui Codjo Kouassi, D. S. Karou |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | European Scientific Journal ESJ. 16 |
| ISSN: | 1857-7431 1857-7881 |
| Popis: | Introduction: Un depistage fiable de l’anemie dans un contexte d’urgence grâce a un hemoglobinometre de biologie delocalisee demeure un defis en Afrique. Le but de cette etude etait d’evaluer le degre de concordance des resultats d’hemoglobinemie obtenus sur l’HemoCue® Hb 301 par rapport a ceux de l’analyseur Sysmex XN-1000®. Methodes : Il s’est agi d’une etude retrospective et transversale descriptive realisee du 08 Mai 2017 au 23 Fevrier 2018 au CHU Campus du Togo. La performance du Sysmex XN-1000® a ete confirmee grâce a l’evaluation de l’exactitude et de la fidelite de mesure. La performance de l’Hemocue® Hb 301 a ete evaluee au moyen d’une regression lineaire et du diagramme de Bland et Altman vis-a-vis du Sysmex XN-1000®. Les criteres de performances utilises etaient ceux du Clinical Laboratory Improvement Amendments (CLIA) et de RICOS et al. Resultats: Le niveau d’exactitude selon CLIA du Sysmex XN-1000® etait de 100%. L’equation de la droite de regression etait: Y (HemoCue® Hb 301) = 0,99x (Symex XN-1000®) + 0,54 g/dl. Les valeurs medianes des 100 echantillons sur le Sysmex et l’Hemocue etaient respectivement de 12,55 g/dl et 13,00 g/dl avec un biais median de 3,58%, qui etait inferieur au biais limite de ±7,0% (CLIA). Conclusion: Le Sysmex XN-1000® fournit des resultats d’hemoglobinemie interchangeables avec ceux de l’HemoCue® Hb 301, sans alteration de la capacite diagnostique pour le patient. Il reste donc performant pour un quelconque dosage d’hemoglobinemie en urgence. Introduction: Reliable anemia screening in an emergency setting, using a Point-of-care hemoglobinometer remains a challenge in Africa. The purpose of this study was to assess the degree of agreement between hemoglobin results obtained on the HemoCue® Hb 301 compared to those of the Sysmex XN-1000® Analyzer. Methods: This was a retrospective and cross-sectional descriptive study carried out from May 08 2017 to February 23, 2018 at the Campus teaching hospital of Togo. The performance of the Sysmex XN-1000® was confirmed by evaluating the measurement accuracy and precision. The performance of Hemocue® Hb 301 was assessed using linear regression and a Bland and Altman plot against Sysmex XN-1000®. The performance criteria used were those of Clinical Laboratory Improvement Amendments (CLIA) and RICOS et al. Results: The CLIA level of accuracy of the Sysmex XN-1000® was 100%. The equation for the regression line was: Y (HemoCue® Hb 301) = 0.99x (Symex XN-1000®) + 0.54 g / dl. The median values of the 100 samples on the Sysmex and Hemocue were 12.55 g / dl and 13.00 g / dl respectively, with a median bias of 3.58%, which was less than the borderline bias of ± 7.0 % of CLIA. Conclusion: The Sysmex XN-1000® provides interchangeable hemoglobin results with those of HemoCue® Hb 301, without altering the diagnostic ability for the patient. It therefore remains effective for any emergency dosage of hemoglobinemia. |
| Databáze: | OpenAIRE |
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