Сlinical and prognostic value of total fibrinogen level and its role in heart disorders on the background of different gallbladder conditions
| Autor: | L. M. Strilchuk |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
biology Unstable angina business.industry medicine.disease Fibrinogen Gastroenterology Fibrin Heart disorder Hemostasis Internal medicine medicine biology.protein General Earth and Planetary Sciences Liver function Thrombus business Vasculitis General Environmental Science medicine.drug |
| Zdroj: | Bukovinian Medical Herald. 23:129-135 |
| ISSN: | 2413-0737 1684-7903 |
| DOI: | 10.24061/2413-0737.xxiii.4.92.2019.100 |
| Popis: | Total fibrinogen (TF) is in the focus of attention of scientists and doctors since Hippocrates’ time. Fibrous component of thrombus was for the first revealed in the end of XVII century. Term “fibrin” was introduced in 1801, “fibrinogen” – in 1847, despite the latter was discovered in 1859. Nowadays TF is considered to be not only criterion of inflammation activity, but also a marker of cardiovascular risk. The aim of this study: estimation of the modern condition of the problem of TF analysis and usage according to literature data and own clinical results. Material and methods. We organized a literature search in PubMed database and domestic sources. Fibrinogen concentration (gravimetric method of R.A. Rutberg), level of soluble fibrin-monomer complex (SFMC) (Tehnologiya-Standart, Russia) and D-dimers (TECHNOZYM D-dimer ELISA, Austria) were estimated in 489 patients with ischemic heart disease (IHD), hemorrhagic vasculitis (HV), and rheumatic fever (RF) in patients with different gallbladder (GB) conditions. Results were analyzed with the help of variational statistics. Data was considered significant if p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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