Bio-Inspired Segmentation and Detection Methods for Human Embryonic Stem Cells

Autor: Prue Talbot, Bir Bhanu, Benjamin X. Guan, Nikki Jo-Hao Weng
Rok vydání: 2015
Předmět:
Zdroj: Computational Biology ISBN: 9783319237237
DOI: 10.1007/978-3-319-23724-4_7
Popis: This paper is a review on the bio-inspired human embryonic stem cell (hESC) segmentation and detection methods. Five different morphological types of hESC have been identified: (1) unattached; (2) substrate-attached; (3) dynamically blebbing; (4) apoptotically blebbing; and (5) apoptotic. Each type has distinguishing image properties. Within each type, cells are also different in size and shape. Three automatic approaches for hESC region segmentation and one method for unattached stem cell detection are introduced to assist biologists in analysis of hESC cell health and for application in drug testing and toxicological studies.
Databáze: OpenAIRE