Hydroxyapatite For Poly(α-Hydroxy Esters) Biocomposites Applications
Autor: | Hon-Meng Ng, Soo Tueen Bee, Abdul Razak Rahmat, Chantara Thevy Ratnam, Lee Tin Sin |
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Rok vydání: | 2018 |
Předmět: |
Filler (packaging)
Materials science Polymers and Plastics Composite number Biomedical Engineering 02 engineering and technology engineering.material Matrix (biology) 010402 general chemistry 01 natural sciences Bone tissue engineering stomatognathic system Materials Chemistry Ceramic Electrical and Electronic Engineering chemistry.chemical_classification Renewable Energy Sustainability and the Environment General Chemistry Polymer Biodegradation 021001 nanoscience & nanotechnology 0104 chemical sciences Electronic Optical and Magnetic Materials chemistry Chemical engineering visual_art engineering visual_art.visual_art_medium Biopolymer 0210 nano-technology |
Zdroj: | Polymer Reviews. 59:187-239 |
ISSN: | 1558-3716 1558-3724 |
DOI: | 10.1080/15583724.2018.1488729 |
Popis: | This article focuses on providing a systematic review on various fundamental properties of composite based on poly(α-hydroxy esters) and hydroxyapatite (HAp) for application in bone tissue engineering. Poly(α-hydroxy esters), a well-known synthetic biopolymer has attracted considerable interest to be employed for synthesis of bone graft substitute material with HAp mainly due to its bioresorbability, variable biodegradation rate and melt-processibility. Such features are simultaneously attractive for both biomedical application and industrial-scale productions. Besides the main function of hydroxyapatite as bioactive ceramic filler in composite to induce new bone formation upon polymer bioresorption, HAp can also serve as reinforcement for matrix polymer by providing sufficient mechanical support for cell attachment. Moreover, HAp plays a significant role in determining other composite properties, such as resistance to ingress of body fluid, body temperature ageing, relaxation movement of polymer ... |
Databáze: | OpenAIRE |
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