| Autor: |
Davydov, G.A., Sigov, M.A., Davydova, E.V. |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| DOI: |
10.34660/inf.2023.38.73.134 |
| Popis: |
Dynamic liver scintigraphy with technetium-99m labeled hepatotropic radiopharmaceuticals (RP) is an important method for assessing the functional state of the liver and determining the risk of a formidable complication in the form of postoperative liver failure during surgical interventions, especially extensive liver resection. The article is devoted to determining the most informative indicators of the quantitative assessment of liver function according to dynamic hepatoscintigraphy using 99mTc-mebrofenin and 99mTc-phytate. The analysis showed a strong correlation between the liver clearance index according to Ekman et al. (1996) with the percentage of radiopharmaceutical uptake by the liver according to SPECT/CT data, which justifies its adequacy for quantitative assessment of liver function. Traditional amplitude-time indicators characterizing the rate of increase in the “time-activity” curve in the liver region and the ratio of its amplitude to the background, weakly correlated with the level of radiopharmaceutical uptake in the liver, so they cannot serve as reliable criteria for assessing liver function. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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