The bronchodilator test in patients with airway obstruction: the responsiveness of lung function parameters
| Autor: | L. A. Popova, M. I. Chushkin, N. L. Karpina, E. A. Shergina |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Spirometry
medicine.medical_specialty medicine.diagnostic_test business.industry medicine.drug_class respiratory system Airway obstruction medicine.disease respiratory tract diseases Pulmonary function testing 03 medical and health sciences FEV1/FVC ratio 0302 clinical medicine Airway resistance 030228 respiratory system Internal medicine Bronchodilator medicine Cardiology Lung volumes 030212 general & internal medicine business Specific Airway Resistance |
| Zdroj: | Medical alphabet. :57-61 |
| ISSN: | 2078-5631 |
| DOI: | 10.33667/2078-5631-2021-5-57-61 |
| Popis: | Interpretation of bronchodilator (BD) test based on reaction of forced expiratory in one second (FEV 1). For assessing bronchodilator responsiveness of lung volumes, airway resistance remains largely unexplored. Therefore, we assessed the response of pulmonary function parameters to BD to reveal the most responsive parameter. 90 patients with chronic airway obstruction (61 male and 29 female; aged 55±11; post- BD FEV 1 was 63.1+18.3 % predicted) performed spirometry and static lung volume measurements before and after inhalation of BD. We calculated effect size (ES) for each parameter from the difference between two means divided by the standard deviation of baseline score. There was a significant increase both FVC and FEV 1by 8.2 and 12.3 % from baseline (p |
| Databáze: | OpenAIRE |
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