Role of SPECT-CT in sentinel lymph node biopsy in patients diagnosed with head and neck melanoma
| Autor: | P. Fernández-Ortega, E. López-Rodríguez, Francisco Javier García-Gómez, R.M. Álvarez-Pérez, I. Borrego-Dorado, R. Martínez-Castillo, T. Zulueta-Dorado |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Surgical approach medicine.diagnostic_test business.industry Melanoma Sentinel lymph node General Engineering Retrospective cohort study medicine.disease Preoperative care 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Biopsy medicine General Earth and Planetary Sciences In patient Radiology business Head and neck General Environmental Science |
| Zdroj: | Revista Española de Medicina Nuclear e Imagen Molecular (English Edition). 35:22-28 |
| ISSN: | 2253-8089 |
| Popis: | Objective Assess the role of SPECT-CT in sentinel lymph node (SLN) biopsy in the accurate anatomical location of the SNL in patients with cutaneous head and neck melanoma. Material and methods A retrospective study was conducted from February 2010 to June 2013 on 22 consecutive patients with a diagnosis of cutaneous head and neck melanoma (9 female, 13 male), with a mean age of 55 years old and who met the inclusion criteria for SLN biopsy. Patients underwent preoperative scanning after peri-scar injection of 99mTc-labeled-nanocolloid. Planar images of the injection-site, whole-body, and SPECT-CT scanning were acquired. Results Detection rate of SLN reached up to 91% (20/22 patients) by planar lymphoscintigraphy and 95.4% (21/22 patients) by SPECT-CT. SPECT-CT provided an accurate location of SLN in 14/22 patients, enabling to improve the surgical approach (clinical impact: 63.6%). SLN was positive for metastatic cells in 9.1% patients. Conclusion SPECT-CT provides detailed anatomical SLN location and allows detecting a higher number of SLN than planar lymphoscintigraphy. Routine use of SPECT-CT is recommended in order to optimize the SLN detection and location in patients with head and neck melanoma. |
| Databáze: | OpenAIRE |
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