| Autor: |
Joshi, Amit, Wassenhove, Lauren, Logas, Kelsey, Paras Minhas, Andreasson, Katrin, Weinberg, Kenneth, Che-Hong Chen, Mochly-Rosen, Daria |
| Předmět: |
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| Popis: |
Additional file 2: Figure S2. ALDH2 plays a critical role in regulating cell health in Alzheimer’s disease patient fibroblast. a) Mitochondrial ROS measured using MitoSOX™ in 2 control and 2 AD patient-derived fibroblasts in the presence or absence of Alda-1 (20 μM) 48 h after transfection with ALDH2*2. b) Cellular ATP levels measured using CellTiter-Glo Luminescent Cell Viability kit in 2 control and 2 AD patient-derived fibroblasts in the presence or absence of Alda-1 (20 μM) 48 h after transfection with ALDH2*2. Data information: Mean, standard deviation, and p-values are shown. Results are presented as fold change. n = 3–7 independent biological replicates; probability by one-way ANOVA (with Holm-Sidak post hoc test). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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