Hydrolysis of 3,4-diphenyl-1,2,5-thiadiazole-1,1-dioxide. Acid and base catalysis

Autor:	J. E. Sicre, E. J. Vasini, M. V. Mirifico
Rok vydání:	1991
Předmět:	Organic Chemistry Inorganic chemistry Substrate (chemistry) Protonation Biochemistry Catalysis Inorganic Chemistry chemistry.chemical_compound Hydrolysis Reaction rate constant chemistry Ionic strength Benzil Physical and Theoretical Chemistry Equilibrium constant
Zdroj:	International Journal of Chemical Kinetics. 23:197-202
ISSN:	1097-4601 0538-8066
Popis:	We have performed a product and kinetic study of the hydrolysis of 3,4-diphenyl-1,2,5-thiadiazole-1,1-dioxide in aqueous solution. Benzil and sulfamide are the only products of hydrolysis and are formed in equimolar yields. The kinetic results indicate that a first order law is followed up to 90% conversion. The observed rate constant is independent of substrate concentration. Ionic strength and buffer concentration do not affect the rate constant, but the reaction is acid-base catalyzed. The rate-pH profile has been determined and a mechanism that fits the experimental data satisfactorily is proposed. Corresponding rate constants and equilibrium constants for the protonation of the substrate are reported.
Databáze:	OpenAIRE
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