Disease Activity Score (DAS) Correlation to Serum Prolidase as a Collagen Turnover Marker in Comparison to Some Pro-inflammatory Markers in Rheumatoid Arthritis Patients: Clinical and Sonographic Study

Autor: Riham Ahmed, Nema Soliman
Rok vydání: 2023
Předmět:
Zdroj: Journal of Advances in Medicine and Medical Research. 35:14-24
ISSN: 2456-8899
Popis: Objectives: Disease activity score (DAS) correlation to serum prolidase in comparison to other pro-inflammatory markers in rheumatoid arthritis (RA) cases. Method: Forty RA cases and 40 age and sex matched controls were studied in this case-control study. Cases fulfilled the 2010 American college of rheumatology (ACR)/ European League Against rheumatism (EULAR) RA classification criteria. Disease activity was assessed by the disease activity score 28 (DAS 28). Ultrasound (US) scanning of synovitis in pre-selected joint was done in both gray scale (GS) and power doppler US (PDUS) modes. Results: The cases’ mean age was 50.05 ± 7.99 years, 52 females and 28 males participated in this study. The mean disease duration was 6.10 ± 3.89 years and the mean for the DAS-28 score was 4.85 ± 1.04. There was a significant correlation between CRPM and DAS 28 score (r=0.323, p=0.042). IL-6 correlated with GS synovitis in the wrist (r=0.376, p= 0.017), MCP (r=0.430, p= 0.006) and PIP (r=0.653, p=
Databáze: OpenAIRE