| Popis: |
Several studies have confirmed that patients with vasospastic angina have a variable ischemia threshold for exercise [1–3]. In our group, Molinero has demonstrated [4, 5] that variable ischemia threshold, identified by different serial electrocardiographic effort tests, is frequent (12/20 cases) in patients with angina at rest and with exertion (mixed angina). Servi [1] identified a significant increment in exercise tolerance and regional coronary flow after administration of nifedipine in patients with effort angina and variable electrocardiographic threshold. Parting from these findings, our study had a double objective: a) identification of the vasospastic component of effort angina by evaluating coronary reserve, and b) appraisal of the therapeutic value of identifying this component. |
