Delayed hypersensitivity reaction caused by metal-on-metal total disc replacement

Autor: Richard Assaker, Jean Michel Remacle, Fahed Zairi, Mohamed Allaoui
Rok vydání: 2013
Předmět:
Zdroj: Journal of Neurosurgery: Spine. 19:389-391
ISSN: 1547-5654
DOI: 10.3171/2013.6.spine121010
Popis: The authors report the case of a 53-year-old woman who underwent placement of a metal-on-metal total disc replacement (TDR) device for the treatment of discogenic back pain. The initial postoperative course was normal, but 2 months after surgery she started to complain of a recurrence of pain and she progressively developed cauda equina syndrome. Radiological and biological findings showed an inflammatory polyneuropathy associated with an epidural mass. A diagnosis of cell-mediated hypersensitivity reaction (Type IV) was made after patch testing showed positive reactions for 1% cobalt chloride and chromium. A decision was made to remove the TDR device and to perform a circumferential fusion. This report is intended to inform the reader that systemic metal release and hypersensitivity reaction are possible complications of metal-on-metal TDR.
Databáze: OpenAIRE