Reaction Calorimetry in Microreactor Environments—Measuring Heat of Reaction by Isothermal Heat Flux Calorimetry
| Autor: | Gabriel Glotz, Philip Podmore, Heidrun Gruber-Woelfler, C. Oliver Kappe, Donald J. Knoechel |
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| Rok vydání: | 2017 |
| Předmět: |
Exothermic reaction
010405 organic chemistry Chemistry Organic Chemistry Analytical chemistry Calorimetry 010402 general chemistry Static mixer 01 natural sciences Isothermal process 0104 chemical sciences law.invention Calorimeter Heat flux Reaction calorimeter law Physical and Theoretical Chemistry Microreactor |
| Zdroj: | Organic Process Research & Development. 21:763-770 |
| ISSN: | 1520-586X 1083-6160 |
| DOI: | 10.1021/acs.oprd.7b00092 |
| Popis: | A novel setup to analyze the heat of reaction of different single- and multiphase reactions carried out in continuous flow is presented. The measurement principle of the calorimetric system is based on true heat flow measurements and therefore ensures precise calorimetric data within 10 mW resolution. In addition to the investigation of simple mixing phenomena (ethylene glycol and water), a number of exothermic, industrially relevant chemical transformations including the nitration of phenol, the reduction of nitrobenzene, as well as several oxidation and reduction processes, were investigated as model systems. For these experiments a commercially available batch calorimeter (ChemiSens CPA202) was equipped with a glass static mixer (250 μL) optionally connected to a tubular microreactor (PFA coil) allowing overall reaction volumes of up to ca. 5.5 mL. Experiments were performed by feeding individual streams with syringe pumps (alternatively substituting one liquid feed with a gaseous feed controlled by a ... |
| Databáze: | OpenAIRE |
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