Synthesis, Characterization, Crystal, and Molecular Structure Analysis of 3,4-dihydro-6-(2-hydroxyphenyl)-5-nitro-4-phenylpyrimidin-2(1H)-one

Autor:	Sridhar M. Anandalwar, L. B. Gowda, Anamik Shah, Javaregowda S. Prasad, M. M. Savant, Yogesh T. Naliapara
Rok vydání:	2015
Předmět:	Pyrimidine Hydrogen bond Stereochemistry Cyclohexane conformation General Chemistry Condensed Matter Physics Ring (chemistry) Medicinal chemistry Benzaldehyde chemistry.chemical_compound chemistry Nitro Molecule General Materials Science Monoclinic crystal system
Zdroj:	Molecular Crystals and Liquid Crystals. 609:118-125
ISSN:	1563-5287 1542-1406
DOI:	10.1080/15421406.2014.928425
Popis:	A novel nitro and 2-hydroxyphenyl functionalized pyrimidinone at C5 and C6, respectively, has been synthesized using 1-(2-hydroxyphenyl)-2-nitroethanone, benzaldehyde, urea, and etidronic acid as a catalyst is described. The synthesized compound characterized by spectroscopic techniques and finally confirmed by X-ray diffraction studies. The molecule crystallizes in the monoclinic crystal class in the space group P21/c with cell parameters a = 11.1070(10)A, b = 8.8210(4)A, c = 15.1110(13)A, β = 106.193(2)°, and Z = 4. The pyrimidine ring adopts flattened boat conformation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4e04edce1c2ed07b61f40e435ab6b75d https://doi.org/10.1080/15421406.2014.928425 Zobrazit plný text záznamu