Biosynthesis of , a putative C5 intermediate in the mevalonate independent pathway for isoprenoid biosynthesis

Autor:	Catherine Pale-Grosdemange, Michel Rohmer, Jean-Michel Bravo, Tore Duvold
Rok vydání:	1997
Předmět:	biology Stereochemistry Organic Chemistry Corynebacterium ammoniagenes Erythritol biology.organism_classification Biochemistry Isoprenoid biosynthesis chemistry.chemical_compound Biosynthesis chemistry Glyceraldehyde Labelling Drug Discovery Non-mevalonate pathway Bacteria
Zdroj:	Tetrahedron Letters. 38:4769-4772
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(97)01045-9
Popis:	According to incorporations of 13 labelled glucose, 2-C-methyl-d-erythritol was most likely synthesized by Corynebacterium ammoniagenes from glyceraldehyde 3-phosphate and from pyruvate via a condensation and a rearrangement. The observed labelling patterns for methylerythritol were identical with those of the isoprenic units of dihydromenaquinones from the same bacterium, suggesting for this tetrol an intermediate role in the non-mevalonate pathway for isoprenoid biosynthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4dec2d2f190d970cb831b109e24d7af0 https://doi.org/10.1016/s0040-4039(97)01045-9 Zobrazit plný text záznamu Full Text from ScienceDirect