BCG-LYMPHADENITIS IN CHILDREN WITH CHRONIC GRANULOMATOUS DISEASE. 74

Autor:	Vl Spassov, S Lalchev, M. Sarbinova, Iv Strarbanov, Bobev D
Rok vydání:	1997
Předmět:	medicine.medical_specialty Lung Anemia business.industry Hepatosplenomegaly Disease medicine.disease Dermatology Immune system Otitis Chronic granulomatous disease medicine.anatomical_structure Pediatrics Perinatology and Child Health Immunology medicine Lymph medicine.symptom business
Zdroj:	Pediatric Research. 41:757-757
ISSN:	1530-0447 0031-3998
DOI:	10.1203/00006450-199705000-00093
Popis:	For the period 1994-1996, five boys with x-linked recessive form of chronic granulomatosis disease (CGD) were diagnosed and treated in Children's Oncohematology Clinic in Sofia, Bulgaria. The patients were hospitalized for anemia and marked hepatosplenomegaly. All 5 patients had BCG-lymphadenitis and some of them had fistulisation of the lymph nodes. The history of relapsing skin and lung infections, otitis and torpid evolution of a specific lymphadenitis raised the clinical suspicion of CGD. Primary immune deficiency in phagocytosis was documented with a positive NBT-test in all 5 patients, their mothers and some of their relatives.
Databáze:	OpenAIRE
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