Thromboelastographic method for early decision on anticoagulant therapy in moderate to severe COVID-19 patients
| Autor: | Komang Ayu Ferdiana, Andi Ade Wijaya Ramlan, Ratna Farida Soenarto, Anas Alatas |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Medical Journal of Indonesia. 31:96-101 |
| ISSN: | 2252-8083 0853-1773 |
| Popis: | BACKGROUND Coagulopathy is a serious COVID-19 complication that requires rapid diagnosis and anticoagulation. This study aimed to determine the role of coagulation examination using thromboelastography (TEG) on the decision-making time of anticoagulant therapy in COVID-19 patients and its clinical outcomes. METHODS A prospective observational study was conducted in Cipto Mangunkusumo Hospital, Indonesia, from October 2020 to March 2021. We consecutively recruited moderate and severe COVID-19 patients in the high and intensive care units. Turnaround time, time to anticoagulant therapy decision, and clinical outcomes (length of stay and 30-day mortality) were compared between those who had a TEG examination in addition to the standard coagulation profile examination (thrombocyte count, PT, APTT, D-dimer, and fibrinogen) and those who had only a standard coagulation profile laboratory examination. RESULTS Among 100 moderate to severe COVID-19 patients recruited, 50 patients had a TEG examination. The turnaround time of TEG was 45 (15–102) min versus 82 (19–164) min in the standard examination (p |
| Databáze: | OpenAIRE |
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