| Autor: |
Sònia Jaraba, J. Mora, Misericordia Veciana, Jacint Sala-Padró, Vendrell Am, Mercè Falip, Gabriel Reynés-Llompart |
| Rok vydání: |
2020 |
| Předmět: |
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| Popis: |
Background: The diagnosis of non-convulsive status epilepticus (NCSE) in patients with non-epileptiform EEG patterns remains a challenge. Objective: To prove the usefulness of single photon emission computerized tomography (SPECT) and its quantification (QtSPECT) in co-localizing the abnormal focus in the EEG with an area of hyperperfusion, thus helping in the diagnosis of NCSE.Methods: We retrospectively reviewed patients admitted with clinical suspicion of NCSE who underwent an HMPAO-SPECT controlled by scalp-EEG showing non-epileptiform patterns, in a 5-year period. We divided our patients in confirmed NCSE (n=11) and non-NCSE (n=8), and compared the EEG and SPECT results in both groups.Results: Lateralized rhythmic delta activity (LRDA) was predominant in the NCSE group (45’4%, p=0’045), while lateralized irregular slowing was observed equally in both groups. Patients with NCSE showed significant hyperperfusion compared to non-NCSE patients (p=0.026). QtSPECT correctly classified 91% of patients in NCSE and 75% patients with non-NCSE (p=0.006).Conclusions: Regional cerebral blood flow measured with SPECT could be useful in the diagnosis of NCSE in cases of an EEG pattern with lateralized slow activity and high clinical suspicion. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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