Time course of changes in carbohydrate and lipid metabolic parameters in patients with hypertensive disease during therapy with Rilmenidine versus Atenolol

Autor:	Ye. V. Shlyakhto, Ye. K. Shavarova, A. A. Shavarov, Yu. R. Kasherininov, Alexandra Konradi
Rok vydání:	2004
Předmět:	Hypertensive disease business.industry Time course Internal Medicine medicine In patient Pharmacology Carbohydrate Cardiology and Cardiovascular Medicine Atenolol business Rilmenidine medicine.drug
Zdroj:	"Arterial’naya Gipertenziya" ("Arterial Hypertension"). 10:28-32
ISSN:	2411-8524 1607-419X
DOI:	10.18705/1607-419x-2004-10-1-28-32
Popis:	The study has evaluated the impact of 26-week therapy with Rilmenidine, 1-2 mg daily, versus atenolol, 50-100 mg daily, on the parameters of 24-hour blood pressure monitoring, on the results of lipid phenotyping and oral glucose test in 37 patients with mild and moderate arterial hypertension (Stage II) during the randomized study. The antihypertensive effects of the drugs were comparable with a more significant decrease in heart rate in the atenolol group. At the same time, Rilmenidine showed good effects on the parameters of lipid metabolism and on the results of oral glucose tests as compared with atenolol whereas therapy with the latter resulted in deterioration of the blood lipid spectrum.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4dd85398653f91c5f704ba74281d0864 https://doi.org/10.18705/1607-419x-2004-10-1-28-32 Zobrazit plný text záznamu