The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

Autor: Pietro Marini, Francesca Comelli, Daniela Parolaro, Vincenzo Di Marzo, Daniele Bolognini, Maria Grazia Cascio, Barbara Costa, Sabatino Maione, Lisa Anne Gauson, Roger G. Pertwee, Ruth A. Ross
Rok vydání: 2010
Předmět:
Zdroj: British Journal of Pharmacology. 160:677-687
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.2010.00756.x
Popis: Background and purpose: The phytocannabinoid, Δ9-tetrahydrocannabivarin (THCV), can block cannabinoid CB1 receptors. This investigation explored its ability to activate CB2 receptors, there being evidence that combined CB2 activation/CB1 blockade would ameliorate certain disorders.
Databáze: OpenAIRE