HCV-ІНФЕКЦІЯ Й ЛІМФОПРОЛІФЕРАЦІЯ (ОГЛЯД ЛІТЕРАТУРИ)

Autor:	V. T. Kiriienko, O. I. Hlukhova, I. A. Zaitsev, S. Yu. Hryshchenko, V. V. Potii
Rok vydání:	2016
Předmět:	business.industry virus diseases Lymphoproliferative disorders medicine.disease Cryoglobulinemia digestive system diseases Lymphoma Pathogenesis Purpura immune system diseases hemic and lymphatic diseases Immunology Mixed cryoglobulinemia medicine medicine.symptom Vasculitis business
Zdroj:	Вісник наукових досліджень.
ISSN:	2415-8798 1681-276X
DOI:	10.11603/2415-8798.2016.3.6958
Popis:	The article describes the role of HCV-infection in the development of lymphoproliferative disorders, some elements of the pathogenesis of extrahepatic manifestations, such as autoimmune disorders and non-Hodgkin's lymphoma (NHL) associated with HCV infection. Mixed cryoglobulinemia is the most common condition associated with HCV-induced lymphoproliferation and in some cases can lead to clinical manifestations such as hemorrhagic vasculitis, purpura, arthralgia, etc., as well as the development of В -cell NHL. HCV-lymphogenesis is based on continuous B-cell activation and inhibition of B-cell apoptosis, which is likely to play a key role in the development of extrahepatic manifestations associated with HCV-infection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4dd4f76d13503e25b5730688969ea679 https://doi.org/10.11603/2415-8798.2016.3.6958 Zobrazit plný text záznamu