Stem Cell Therapy Combined with Myocardial Revascularization: A Pilot Study using the Harvest Technique
| Autor: | Ahmad A Hassouna, Ezzeldin A Mostafa, Magdy Mm Aly, Motaz Sobhi, Mohammad Ms Elfiky |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Ejection fraction Interventional cardiology medicine.diagnostic_test business.industry medicine.medical_treatment Atrial fibrillation medicine.disease Revascularization Surgery Coronary artery disease Internal medicine Angioplasty Coronary stent medicine Cardiology business Electrocardiography |
| Zdroj: | Journal of Cardiology & Current Research. 5 |
| ISSN: | 2373-4396 |
| DOI: | 10.15406/jccr.2015.05.00151 |
| Popis: | Background: To assess the usefulness of intra-myocardial autologous stem cell injection as a hybrid procedure with coronary artery bypass grafting (CABG) compared to conventional CABG only in the patients with ischemic heart disease with non-viable or non-graftable myocardial segments. Methods: After approval of Local Ethics Committee and obtaining written informed consent, a prospective, comparative randomized study was conducted on 30 ischemic heart patients with non-viable or non-graftable segments. They were divided into two groups. Group A (15 patients): where intra myocardial injection of autologous bone marrow mononuclear cells (ABM-MNCs) was done in conjunction with CABG. Group B (15 patients): where CABG was performed only. Resting and stress echocardiography follow up was done for 6 months. Results: There was no mortality in either group. No complications were noted at a mean of 6 months after surgery. Group A showed a significant improvement (mean of 7.25% and P |
| Databáze: | OpenAIRE |
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