Relationship between Interleukin-18 (IL-18) level and Mean Platelet Volume (MPV) with ischemic stroke event in Sanglah General Hospital, Bali, Indonesia

Autor:	Desak Gde Diah Dharma Santhi, Anak Agung Ngurah Subawa, Dewa Putu Gde Purwa Samatra
Rok vydání:	2020
Předmět:	medicine.medical_specialty business.industry Internal medicine Event (relativity) Ischemic stroke Cardiology Medicine Interleukin 18 General Medicine Mean platelet volume General hospital business
Zdroj:	Bali Medical Journal. 9:477-481
ISSN:	2302-2914 2089-1180
Popis:	Background: Long-term stroke risk factors may lead to inflammation of endothelial vessels characterized by migration of macrophages and T-lymphocytes in blood vessel walls by releasing Interleukin-18 (IL-18) cytokines and causing changes in Mean Platelet Volume (MPV) values. This study aims to determine the relationship between IL-18 and MPV levels with ischemic stroke event in Sanglah General Hospital Denpasar. Methods: A matched-pair case-control study design was conducted in this study. The number of stroke and control samples were 33 people, respectively, and the dependent variable was an ischemic stroke, following MPV and IL-18 as dependent variables. Free T-2 sample test used to compare MPV in each group while the Mann-Whitney test used to compare the interleukin levels of the two groups. Data were analyzed using SPSS version 20 for Windows.Results: The MPV value of ischemic stroke patients was significantly higher (8.5±1.19 fL), whereas the MPV value at control was 0.00±0.44 fL (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4db7bbea6d4437d2f85cd45523b8c2e8 https://doi.org/10.15562/bmj.v9i2.1869 Zobrazit plný text záznamu