Cytologic features of deep juvenile xanthogranuloma
| Autor: | Robert E. Cilley, Catherine Abendroth, Joshua Z. Sickel, Ronald T. Grenko |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Pathology
medicine.medical_specialty Histology medicine.diagnostic_test Juvenile xanthogranuloma business.industry General Medicine medicine.disease Pathology and Forensic Medicine Supraclavicular lymph nodes Lesion medicine.anatomical_structure Fine-needle aspiration Giant cell Cytopathology Touton giant cell medicine medicine.symptom business Histiocyte |
| Zdroj: | Diagnostic Cytopathology. 15:329-333 |
| ISSN: | 8755-1039 |
| DOI: | 10.1002/(sici)1097-0339(199611)15:4<329::aid-dc15>3.0.co;2-q |
| Popis: | Juvenile xanthogranuloma (JXG) is a rare lesion of the skin and deep tissues whose cytologic features have not previously been published. We report on 2 cases of JXG in patients aged 5 days and 5 yr who presented with an axillary mass and enlarged supraclavicular lymph node, respectively. Fine-needle aspiration and touch imprints made from the surgical biopsies yielded cellular specimens composed of histiocytes, multinucleated Touton-type giant cells, and variable admixtures of lymphocytes and eosinophils. One lesion was composed primarily of benign-appearing histiocytes with admixed multinucleated giant cells and a few lymphocytes. The second lesion consisted of a few histiocytes, occasional Touton giant cells, many lymphocytes, and scattered fibroblasts. The histiocytes were CD68-positive and S100-negative. Histologic follow-up confirmed the diagnosis of juvenile xanthogranuloma. One patient was lost to follow-up; the other is alive without evidence of recurrence 1 yr after surgery. We conclude that deep JXG has characteristic and diagnostic cytologic features. |
| Databáze: | OpenAIRE |
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