A silyl-?-cyclodextrin intermediate. Preparation and characterization of dodeca-t-butyldimethylsilyl-hexahydroxy-?-cyclodextrin

Autor:	Ady Kendler, Myron L. Bender, Tomasz J. Michalski
Rok vydání:	1983
Předmět:	chemistry.chemical_classification Cyclodextrin Silylation Cyclohexaamylose General Chemistry Nuclear magnetic resonance spectroscopy Condensed Matter Physics Medicinal chemistry Chloride chemistry.chemical_compound chemistry Pyridine medicine Organic chemistry Food Science medicine.drug
Zdroj:	Journal of Inclusion Phenomena. 1:125-128
ISSN:	1573-1111 0167-7861
DOI:	10.1007/bf00656814
Popis:	The title compound (II) was prepared by treating dry, purified α-cyclodextrin with 20 equivalents oft-butyldimethylsilyl chloride 20 hr at 110° in DMF/pyridine. Work-up of the product mixture gave 60%II, which was identified by1H and13C NMR. Treatment ofII with Bu4NF 6 hr in refluxing dry THF efficiently removed the protecting groups.
Databáze:	OpenAIRE
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